M.A. Thesis:

Preparation of a nano-capsule based on gum tragacanth hydrogel containing Trachyspermum ammi essential oil and its antioxidant, antibacterial and anticancer properties.

Today, not only in Iran, but throughout the world, the tendency toward herbal medicine has increased. Medicinal plants are rich from compounds that have properties, including antibacterial, antioxidant, anti-cancer, and ... . Due to the need to use these compounds and its valuable benefits for humans, extraction and application of medicinal plant extracts was considered. Therefore, it is necessary to find a suitable method for using the medicinal properties of these plants in order to maintain its quality. The purpose of this study was to provide nano-capsule containing essential oils using hydrogel Astraglus gossypinus and to study the antioxidant, anti-bacterial and anti-cancer properties. The Trachyspermum copticum is one of the medicinal plante that has many healing properties, including anti-flatulence, anti-nausea, sputum, and relief of rheumatic pains. To carry out this research, the essential oil was extracted and then used as a nano-capsule using the hydrogel Astraglus gossypinus. in this study, the anti-microbial effects of different extracts of this plant on gram positive and negative bacteria were evaluated using diffusion discs And its antioxidant property was tested using DPPH. Also, the inhibitory effects of nanocapsules on cancer cells were studied. For this purpose, the cells were exposed to different concentrations of plant extracts during different time periods. Then, microscopic and MTT assays were performed to evaluate the cytotoxic effects of plant extract

Keywords: : Nanocepseul, Trachyspermum copticum , Hydrogel, Antibacterial, Antioxidant, Anticancer