M.A. Thesis:

effect of Equisetum arvense extract on coagulation tests

Hemophilia is a disease with bleeding disorders and for its treatment, various methods such as gene therapy, cell therapy, alternative therapy, etc. are used. There are many reports about the effects of different herbs on blood clotting and therefore the treatment of hemophilia. Therefore, in this study, the effect of horsetail on blood coagulation process was investigated. Different concentrations of alcoholic extracts of leaves, stems and leaf and stem combinations were prepared and then coagulation experiments were performed on them. Extraction was performed by ethanol extraction technique with the help of ethanol and ultrasonic device and then certain concentrations were obtained from different organs of the plant. The concentrations used in this experiment were equivalent to the concentrations of 8 g / l, 4 g / l and 16 g / l. Experiments were performed on APTT and PT coagulation indices against the control group and the results showed that horsetail plant extract reduced coagulation time in APTT test to at least 14 seconds at a concentration of 8 g / l and coagulation time in PT test. It takes about 12 seconds at a concentration of 16 grams per liter. In this .

Keywords: experiment, it was found that horsetail plant extract can be very effective during coagulation