M.A. Thesis:

Investigation mineral and antioxidant activity in Cirsium extract (Circium Congestin)

Free radicals cause many diseases in humans. Antioxidants neutralize free radicals with one hand to reduce the risk of cardiovascular disease and stroke, and on the other hand they prevent the progression of cancer here are several ways to prevent oxidation that one of these is the addition of synthetic antioxidants. But according to the synthetic antioxidants adverse effects as a result of mutagenesis and carcinogenesis in the human body, so investigate sources of natural antioxidants to replace synthetic ingredients seem essential. In this study, the freeze-dried artichoke plants with three solvents water, methanol and ethanol were extracted. Then extract the polyphenolic compounds and free radical scavenging power 500,250,150,50 topic ppm concentrations Folin test Syvkaltyvv DPPH, measuring iron was measured. The results showed that with increasing concentration of artichoke extract, phenolic content and inhibitory activity increased significantly Dad.byshtryn amount of phenolic compounds in the sample Mnjmdsarh artichoke methanol at a concentration of 250 ppm and the highest inhibitory activity of free radicals in the sample concentration of 1000 ppm Kngrba blue Mnjmdsarh Was obtained. The phenolic compounds and inhibition of these extracts with increasing polarity of the solvent increases. Despite the high efficiency of water soluble phenolic compounds less than the methanol extract. The water solvent extraction of solids to dissolve. But all of these compounds are not necessarily phenolic compounds. Plant artichokes are a good source of iron in the sample frozen artichoke .gyah reached the upper limit amount of iron minerals.

Keywords: artichoke, free radical scavenging power, phenolic compounds, iron